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Did the Development Speed Paradox Precipitate the Current Pharmaceutical R&D Productivity Crisis?

Did unthinking attempts to minimize cycle time in R&D in the 1990s precipitate the current pharmaceutical R&D productivity crisis?

The Development Speed Paradox: Pharmaceutical R&D Productivity

Minimizing the cycle time of successful molecules sub-optimized the R&D process, increasing R&D costs, increasing the expected time to market, increasing late-stage attrition and reducing overall R&D productivity.

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